![]() Talk to your healthcare provider if you develop any changes in your sexual function or if you have any questions or concerns about sexual problems during treatment with TRINTELLIX. Symptoms in females may include: decreased sex drive, or delayed orgasm or inability to have an orgasm. Symptoms in males may include: delayed ejaculation or inability to have an ejaculation, decreased sex drive, or problems getting or keeping an erection. Sexual problems: Taking antidepressants like TRINTELLIX may cause sexual problems. A patient questionnaire designed to identify sexual side effects was used in TRINTELLIX studies to determine how many people experienced sexual side effects while taking TRINTELLIX. Voluntary reports of sexual side effects with antidepressants are known to be underreported in part because people may be reluctant to discuss them. When proactively assessed in patients with MDD with normal sexual functioning in seven studies using a self-rated questionnaire, reports of sexual side effects from doses of TRINTELLIX 5 mg, 10 mg, and 20 mg were 16%, 20%, and 29% in men (N=212) respectively and 22%, 23% and 34% in females (N=226) respectively, compared to placebo rates of 14% in males (N=162) and 20% in females (N=135). In 6- to 8‑week clinical studies, up to 5% of Major Depressive Disorder (MDD) patients taking TRINTELLIX voluntarily reported sexual side effects. ![]() Can TRINTELLIX cause antidepressant sexual side effects?Īs with other antidepressants, TRINTELLIX can be associated with sexual side effects during treatment.
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